Jankowski M1, Fulton L2, Sheafor S3, Prescott D2, Khanna C.1,4 - Friendship Hospital for Animals1, Washington D.C., VCA-Veterinary Referral Associates2, Gaithersburg MD, SouthPaws Veterinary Specialists and Emergency Center3, Springfield VA, Pediatric Oncology Branch4, NCI-NIH, Bethesda MD.
INTRODUCTION
Angiogenesis is essential for cancer progression and metastasis. Inhibition of angiogenesis may be an effective treatment for cancers. The anticancer activity of thalidomide has been demonstrated in early human clinical trials. The objectives of this study are: 1) to determine the safety and efficacy of oral thalidomide against measurable canine cancers, 2) to define an …

Chand Khanna DVM, PhD, Diplomat ACVIM (Oncology)
Animal Cancer Institute, LLC
New, effective, and non-toxic treatments are now under investigation in both pet animals and people with cancer. These new treatments have become available through a dramatic increase in our understanding of the basic biology of cancer and the requirements for cancer growth and spread. An essential requirement for cancer growth and spread appears to be the development of new blood vessels (angiogenesis). If a cancer requires new blood vessels in order to progress, then it may be possible to prevent a …

A new option for the treatment of canine lymphoma
Non peer reviewed summary, 2/2002
Chand Khanna DVM, PhD, Dipl ACVIM (Oncology)
Animal Cancer Institute LLC
Lymphoma is the most common malignant cancer treated in veterinary oncology. In dogs, the most common presentation for lymphoma is multiple non-painful enlargements of peripheral lymph nodes. It is most common that dogs with lymphoma present without any clinical signs of illness in spite of these enlarged lymph nodes. In most cases lymphoma is thought of as a disseminated disease, where the malignant lymphocytes exist in many tissues through …