Sample Collection Study For Cavalier King Charles Spaniels, Poodles, and Dachshunds

Dogs are eligible if they have a left-sided systolic heart murmur or do not have a
murmur and are at least 8 years old

ACI is conducting a study that involves collection of blood and saliva samples from
Cavalier King Charles Spaniel (CKCS), Mini/Toy Poodles, and Dachshunds, with/
without Degenerative Mitral Valve Disease (DMVD).

Trial Eligibility:

• Any pure breed Toy/Mini Poodles, Dachshunds, and or CKCS with DMVD
• Any pure breed Toy/Mini Poodles, Dachshunds, and or CKCS that is >8 years of age without DMVD
• Canine has a left-sided systolic heart murmur of any grade

Trial Support

No charge examination. All samples will be collected at no charge.

Trial Participation

Friendship Hospital for Animals
Chesapeake Veterinary Cardiology Associates at The LifeCentre

Oncology Appetite and Quality-of-Life Survey

ACI is conducting a survey of pet owners whose dogs are receiving chemotherapy for the treatment of cancer and the veterinary oncologists providing their medical care with the goal of determining the dogs’ frequency, severity, and duration of reduced appetite, gastroenteritis and altered quality of life. The following populations of dogs will be evaluated:

1. Dogs with any cancer (excluding lymphoma and hemangiosarcoma) receiving chemotherapy (no prednisone)
2. Dogs with lymphoma receiving chemotherapy (no prednisone)
3. Dogs with lymphoma receiving chemotherapy with concurrent prednisone
4. Dogs with hemangiosarcoma receiving doxorubicin chemotherapy following splenectomy (no prednisone)
5. Dogs with any cancer receiving toceranib (no prednisone)
6. Dogs with any cancer that is in complete remission (no prednisone) and is not receiving any therapy that is likely to negatively impact appetite (melanoma vaccine, routine follow-up on long-term cases that previously received chemotherapy or radiation therapy).

Funding

$100 is provided to the client for completion of this 2-week survey

Participation

The following animal hospitals are participating in this survey project:

• Friendship Hospital for Animals (DC)
• The LifeCentre (VA)
• Red Bank Veterinary Hospital (NJ)
• The Veterinary Cancer Center (CT)
• The New England Veterinary Cancer Group (MA)
• MedVet (OH)
• Veterinary Specialty Hospital of the Carolinas (NC)
• Veterinary Cancer Group – Tustin (CA)
• Veterinary Specialty Hospital of San Diego (CA)
• Southern Arizona Veterinary Specialty & Emergency Center (AZ)
• Veterinary Cancer Group – LA (CA)
• Great Lakes Veterinary Specialists (OH)
• New York City Veterinary Specialists (NY)
• University of Wisconsin (WI)

Great Pyrenees with Osteosarcoma

ACI is conducting a study that collects saliva sample, buccal (cheek) swabs, and a small amount of whole blood from Great Pyrenees that are diagnosed with Osteosarcoma. Eligible dogs may be newly diagnosed, currently receiving therapy, or previously treated.

Trial Eligibility:

• Any purebred Great Pyrenees with Osteosarcoma
• Any age, breed, or sex is eligible

Trial Support

This study is a voluntary study for pet owners whose dogs meet the above criteria.

Saliva collection kits and buccal swabs will be provided to pet owners at no charge with sampling and mailing instructions inside. A kit with prepaid return packaging will be mailed to the owners for quick and easy return. Blood samples are requested, but not mandatory. Please contact ACI for information on how a blood samples can be obtained in your area.