Dose-finding evaluation of an oral PARP inhibitor plus COP chemotherapy for dogs with lymphoma
21 May 2009
No Comment
Dog Target Accrual= 9 cases
Status: Closed
Eligibility:
Status: Closed
Eligibility:
* Measurable nodal lymphoma- cytological or histological diagnosis
* All clinical stages but must have nodal involvement – includes relapsed cases
* Favorable performance score
* Recent COP treatment discouraged
Trial Support: Owner is responsible for referral examination and CBC/Chemistry/UA at initial study visit. Study provides full support for radiographs, lymph node biopsies (total of 3), lymph node immunophenotyping, bloodwork required by the study, study drug, COP protocol x 6 weeks, and recheck examinations for the first 6 weeks of the protocol.









Pet owners seeking novel treatment options for animals with serious health conditions find an Animal Clinical Investigation network veterinarian participating in a clinical trial.
Animal Clinical Investigation network veterinarian and pet owner work together to determine whether the pet is eligible for the trial. Eligible pets begin treatment at an ACI network hospital.
Information from the trial is used to help develop new drugs and treatments, providing a source of hope for people whose pets face serious illnesses.