Open Pain Management Studies

A CLINICAL RESEARCH STUDY FOCUSING ON PAIN MANAGEMENT IN DOGS LIVING WITH OSTEOARTHRITIS OF THE ELBOW

January 17th, 2020 Posted by Pain Management 0 thoughts on “A CLINICAL RESEARCH STUDY FOCUSING ON PAIN MANAGEMENT IN DOGS LIVING WITH OSTEOARTHRITIS OF THE ELBOW”

Trial Overview

This study aims to confirm the effectiveness and safety of a new medicine to control pain associated with osteoarthritis of the elbow in dogs. If your dog qualifies for this study, you should expect to stay in the study for 90 days and have 7 scheduled visits with the veterinarian conducting the study. You will also be required to provide weekly behavioral assessments of your dog.

Because this is a study that is intended to support the drug’s approval, it needs to be “controlled”. This means some dogs receive treatment and others undergo the preparation and everything leading up to an injection of the medication, but do not actually receive the medication being tested. This study is also “blinded” or “masked”, meaning neither you nor the veterinarian making observations will know if your dog received the treatment or not until the end of the study. All owners of the untreated dogs will be given an opportunity at the end of the study for their dogs to receive the investigational treatment at no charge.

More than 200 dogs have been treated with the drug in safety studies, including pet dogs with elbow pain. This study is primarily focused on confirming the effectiveness of the drug. All dogs will be closely monitored and treated, in the event of any side effect. Please feel free to discuss any hesitations with the treating veterinarian, and if at any time prior to treatment you decide not to enroll your dog, you can do so at no charge and with no questions asked.


Trial Eligibility

Trained veterinarians at the trial sites will evaluate each dog for eligibility.

  • At least 1 year old.
  • Weighs more than 11 pounds.
  • Confirmed diagnosis of bilateral elbow pain due to osteoarthritis impacting mobility and quality of life.
  • If suffering from additional conditions other than joint pain, those conditions are stable and under medical care.
  • Is not intended for breeding and is not pregnant or lactating.
  • Has not had a medical or surgical procedure in the past 30 days.

 
*Other study criteria may apply. The veterinary investigator will decide if your dog is a good candidate for this study after examination.*


Trial Funding

If qualified, your dog would receive (at no cost to you):

  • Investigational medicine or the procedure without injection of the medication.
  • Study-related exams and tests.
  • Time with a local veterinarian.


Participating Sites

Veterinary Specialty Hospital
10435 Sorrento Valley Rd, San Diego, CA 92121
Phone: (858) 875-7500

Advanced Care Veterinary Services
1609 West Hebron Parkway; Ste 108, Carrollton, TX 75010
Phone: (972) 394-6422

Limestone Companion Animal Hospital
4224 Airport Rd, Bartonville, IL 61607
Phone: (309) 697-8000

Quakertown Veterinary Clinic
2250 N. Old Bethlehem Pike, Quakertown PA 18951
Phone: (215) 536-6245

Bradford Park Veterinary Hospital
1255 E. Independence, Springfield, MO 65804
Phone: (417) 886-0777

BluePearl Pet Hospital
3000 Busch Lake Blvd, Tampa, FL 33614
Phone: (813) 933-8944

BluePearl Pet Hospital
9500 Marketplace Road, Fort Myers, FL 33912
Phone: (239) 947-0588

Midwestern University Companion Veterinary Clinic
5715 W. Utopia Rd., Room 202, Glendale, AZ 85308
Phone: (623) 806-7387

Veterinary Specialty Hospital of the Carolinas
6405-100 Tryon Road, Cary, NC 27518
Phone: (919) 233-4911

Franklin Animal Clinic
2990 N Morton St, Franklin, IN 46131
Phone: (317) 736-9246

Veterinary Specialty and Emergency Clinic
625 Ridge Pike, Building B, Conshohocken, PA 19428
Phone: (484) 567-7998

Animal Care Center
562 East Castle Pines Pkwy #C5, Castle Rock, CO 80108
Phone: (303) 688-3660

SEEKING DOGS FOR ENROLLMENT IN A CLINICAL TRIAL EVALUATING A NOVEL THERAPY FOR THE TREATMENT OF TRANSITIONAL CELL CARCINOMA

October 2nd, 2018 Posted by Bladder Cancer, Pain Management, Pain Studies 0 thoughts on “SEEKING DOGS FOR ENROLLMENT IN A CLINICAL TRIAL EVALUATING A NOVEL THERAPY FOR THE TREATMENT OF TRANSITIONAL CELL CARCINOMA”

Trial Specifics

This trial is designed to evaluate the safety and preliminary pain management and effect of a novel therapy in dogs with bladder transitional cell carcinoma (TCC). A secondary goal is to assess potential anti-cancer effect. The trial involves one-time treatment administered directly into the bladder using a urinary catheter. Dogs may receive a second treatment one month after enrollment if warranted. The treatment will be administered under sedation or general anesthesia. There is no placebo in this trial. An estimated 15 client-owned dogs with will be enrolled. Owners will be required to complete quality of life surveys, collect a daily urine sample for visual analysis, and record the urine collection results in a provided journal. The trial site will train the owners on collection and evaluation techniques. Trial visits include the dog’s initial consultation, treatment day (Day 0), and then recheck visits on Days 7, 14, 28, 56, and 84. Anti-cancer therapies must be discontinued 21 days prior to enrollment. Medications targeted at the treatment of TCC-associated pain, except for CBD and other cannabinoids, are acceptable provided they have been administered for at least 2 weeks prior to enrolling in the study.

Trial Funding

The trial is fully funded for the full trial duration (84 days). Funding includes the initial consultation, the study treatment and administration, thoracic radiographs at the beginning and end of the study, monthly abdominal ultrasounds, recheck visits, trial-required bloodwork, and management of side effects that are thought to be directly related to the trial.

Trial Eligibility

Trained veterinarians at the trial sites will evaluate each dog for eligibility.

Dogs are eligible if they meet the following inclusion criteria:

  • Dog presenting with a diagnosis of TCC exclusively associated with the bladder (metastasis is acceptable).
  • Dog with accompanying lower urinary tract clinical signs associated with bladder cancer.
  • Bladder lesion does not prevent the passage of urinary catheter.


Dogs are not eligible if they meet any of the following exclusion criteria:

  • Dog with urethral or prostatic involvement of TCC.
  • Dog has any underlying disease that will affect the study objectives or patient safety.
  • Dog has evidence of hydronephrosis.
  • Dog has an active urinary tract infection (dogs presenting for screening will have a urine culture performed prior to enrollment).
  • Dog has a urethral obstruction.
  • Dog is pregnant or lactating.
  • Dog is participating in another study.

 

This clinical trial is offered at the following locations:

Hope Veterinary Specialists
40 Three Tun Road
Malvern, PA 19355
610-296-2099

Las Vegas Veterinary Specialty Center
8650 W. Tropicana Avenue, Ste. B-107
Las Vegas, NV 89147
702-871-1152

BluePearl Specialty and Emergency
11950 West 110th St
Overland Park, KS 66210
913-642-9563

The Oncology Service – Dogwood
5918 West Broad St
Richmond, VA 23230
804-716-4710

The Veterinary Cancer Center
129 Glover Ave, Norwalk
Norwalk, CT 06850
203-838-6626

Coming Soon

Nothing at this time.