Trial Overview
This fully funded, randomized, placebo-controlled clinical trial will assess a potential new treatment for oral melanoma in dogs.
Eligibility
- Diagnosis of Stage III oral melanoma (not confined to lip)
- At least one measurable lesion with a longest diameter of ≥ 10 mm (≥ 15 mm short axis for lymph node lesions)
- Prior surgery acceptable (if performed at least 14 days prior to enrollment) if measurable disease remains which meets above criteria
- No lung metastasis
- No prior Oncept® melanoma vaccine
- Dog must weigh at least 3 kg (6.6 lb)
- Other study criteria may apply. The Investigator will decide if the dog is a good candidate for this study after examination.
Trial Details
- Investigational product or placebo once every 2 weeks for approximately 6 months (15 scheduled visits)
- All trial visits must occur at one of the designated trial clinics listed below
- Periodic lab work and thoracic radiographs (x-rays) will be performed to assess each dog’s overall health
- Owners are required to sign a consent form before their dog is enrolled, complete owner diaries at home and complete a single quality-of-life assessment question at each trial visit
- At study end, dogs are eligible to receive the investigational product in a separate clinical trial
Study Sites
Akron, OH
Athens, GA
Dallas, TX
Fort Collins, CO
Madison, WI
Malvern, PA
Middleton, WI
Newtown, CT
Overland Park, KS
Pittsburgh, PA
Richmond, VA
Salt Lake City, UT
San Diego, CA
San Francisco, CA
Springfield, VA
St. Paul, MN
Tacoma, WA
Vienna, VA
Washington, DC
Additional study sites coming soon!
